Skin Alert: What are SKs and why do you need to know about them?

I collaborated with the makers of ESKATA® (hydrogen peroxide) topical solution, 40% (w/w) to create this post


When I first started Prime Beauty, it was about makeup and beauty for over 40 women. As the blog has grown and I’ve gotten older, I’ve expanded the scope to include women’s health issues. I’ve talked about Menopause, Hepatitis C and IBS. Today I’d like to talk about another health issue for older women, seborrheic keratoses or SKs, which are non-cancerous skin growths that can appear as flat or raised and that affect 83 million Americans and can be a concern – especially when on the face, neck and chest. SKs tend to increase in number with age and only a doctor can diagnose SKs.

SKs may be a sign of aging and can be referred to as age spots or barnacles. They can vary in color from flesh colored to pink, yellow, grey, tan, brown or black. SKs frequently appear in highly visible locations, such as the face or neck, but can also appear anywhere on the body, except the palms, soles and mucous membranes. My mother had SKs on her upper arms as she got older and was worried about them. She made sure to always wear sleeves so her SKs wouldn’t show.

Many people with SKs avoid important special events like weddings, graduations, formal events, and holidays because of their SKs, and some cover up to hide them. Now, there is help with ESKATA® (hydrogen peroxide) topical solution, 40% (w/w)!

ESKATA is the first and only FDA-approved topical treatment for raised SKs. ESKATA is a proprietary, high concentration (40%) hydrogen-peroxide based topical solution that is applied directly to the raised SK by a medical professional using a single-use, soft tip pen-like applicator. You won’t believe the difference in these before and after pictures of Kirsten, a REAL patient!

Kirsten BEFORE

Kirsten at 3 Weeks

Kirsten at Day 106 (Final Result)

18% of patients experienced clearance of 3 out of 4 raised SKs treated with ESKATA vs 0% with vehicle (Day 106 end of study). Nearly all patients received 2 treatments. Serious eye problems and severe skin reactions have occurred.  The most common side effects are itching, stinging, crusting, swelling, redness, and scaling. Actual patient. Individual results may vary.

The FDA approval of ESKATA was supported by two clinical trials with over 900 patients; over 1,800 raised SKs have been treated with ESKATA, which constitutes the largest body of research ever performed in patients with raised SKs!

Thankfully, SKs are non-cancerous and generally don’t cause any pain or discomfort. But, if the raised spots on your face or neck are concerning you, the first step is going to your dermatologist to see if they are indeed raised SKs and talk about having them removed.

Go to to learn more about raised SKs and to find a doctor in your area who can tell you if you are a candidate for ESKATA. Stop covering up and get out there!

Important Safety Information and Approved Use

ESKATA can cause serious side effects, including:

  • Eye problems. Eye problems can happen if ESKATATM (hydrogen peroxide) topical solution, 40% (w/w) gets into your eyes, including: ulcers or small holes in your eyes, scarring, redness, irritation, eyelid swelling, severe eye pain, and permanent eye injury, including blindness.
  • If ESKATA accidentally gets into your eyes, your healthcare provider will tell you to flush them well with water for 15 to 30 minutes. Your healthcare provider may send you to another healthcare provider if needed.
  • Local skin reactions. Skin reactions have happened in and around the treatment area after application of ESKATA. Severe skin reactions can include: breakdown of the outer layer of the skin (erosion), ulcers, blisters and scarring. Tell your healthcare provider if you have any skin reactions during treatment with ESKATA.


The most common side effects of ESKATA include: itching, stinging, crusting, swelling, redness and scaling.

Your healthcare provider will not apply another treatment of ESKATA if your treated area is still irritated from the previous treatment.

Tell your healthcare provider right away if ESKATA gets into your eyes, mouth or nose during application.  ESKATA is for topical use on the skin only, and is not for use in your eyes, mouth or vagina.

These are not all the possible side effects of ESKATA.

 Approved Use for ESKATA

ESKATA is a prescription medicine used to treat seborrheic keratoses that are raised.

ESKATA is for use as an in-office treatment. ESKATA is applied by your healthcare provider and is not for use at home.

You are encouraged to report negative side effects of prescription drugs to the FDA. Contact Aclaris Therapeutics, Inc. at 1-833-ACLARIS or 1-833-225-2747 or FDA at 1-800-FDA-1088 or

Click here for Prescribing Information, including Patient Information.

From our partners


  1. Kristy Bullard says

    This is so interesting! I’m going to talk to my dermatologist about this!


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